Urepearl Plus Lotion10


Second-class OTC drug


Medicated Moisturizer for Dry Skin

  • This medicine contains a natural moisturizing factor, urea and vitamin E (tocopheryl acetate) which help to maintain water, and smoothen and moisturize dry skin.
  • It contains two types of components as anti-itching active ingredients.
  • It is a clear and colorless lotion which spreads smoothly.
Packaging Manufacturer's suggested retail price
100mL JPY 2,024
(JPY 1,840 excluding tax)


The following precaution should be observed.
(If not observed, it may aggravate the current symptoms or increase the risk of adverse reactions.)
Do not apply to the following areas.

  1. Around the eyes, mucous membranes (e.g. mouth, nasal cavity, vagina, etc.)
  2. Inflammation or wounds
  3. Severe skin sore or cracking of the skin


  1. The following persons should consult a physician, pharmacist or registered salesperson before using the medicine.
    1. Persons under treatment by a physician
    2. Persons with a history of allergic symptoms (e.g. rash, redness, itching, contact dermatitis, etc.) or irritation symptoms due to any drug
  2. The following symptoms may be adverse reactions to the medicine. If any of these symptoms occur, discontinue the use of the medicine immediately, and consult a physician, pharmacist or registered salesperson with this leaflet.
    Affected body systemSymptoms
    Skin Contact dermatitis, rash, redness, itching, irritation (pain, feeling hot, tingling sensation), swelling, scab-like skin exfoliation
  3. If symptoms do not improve after using the medicine for about two weeks, discontinue the use of the medicine, and consult a physician, pharmacist or registered salesperson with this leaflet.


Dry skin accompanied by itching (xeroderma in the elderly/adults, dry skin in children)


Apply an appropriate amount to the affected area once to several times daily.


  1. Be careful not to get the medicine into the eyes. If the medicine gets into the eyes, immediately wash with water or lukewarm water. If symptoms are severe, consult an ophthalmologist.
  2. For children, use under parental guidance.
  3. For external use only.
  4. Clean the affected area and surrounding skin before use.
  5. Follow the prescribed dosing instructions.
  6. As this is not a cosmetics, use only for the affected areas listed in the indications, and do not use on the face for the purpose of basic skin care, etc.


Each 100 mL contains the following active ingredients.
Urea 10.0 g, Lidocaine 2.0 g, Diphenhydramine Hydrochloride 1.0 g

Inactive ingredients:
Glycerin, Diisopropyl Sebacate, Lactic Acid, Sodium Lactate, Hydroxypropylcellulose, Purified Water, Flavor, Ethanol


  1. Stopper tightly and store in a cool place, away from high temperature and direct sunlight.
  2. Keep out of the reach of children.
  3. Do not transfer to other container. (It may cause misuse or change the quality.)
  4. As the product is combustible, do not bring it close to fire.
  5. Do not throw the empty container into fire.
  6. Avoid the medicine to stick to the items which may melt in alcohol, etc. (eyeglass frame, painted furniture, etc.).
  7. Do not touch the eyes and mucous membrane with hands attached the medicine.
  8. Do not use the product past the expiration date printed on the outer box and the container.


Manufactured and Distributed by: Otsuka Pharmaceutical Factory Inc.
Dosage form Lotion
Packaging unit 100 mL
JAN Code 4987117140323
Expiration 3 years


For inquiries, please contact the shop where you purchased the product or the following:
Distributor Contact: Customer Relations Office, Taiho Pharmaceutical Co., Ltd.
1-27 Kandanishiki-cho, Chiyoda-ku, Tokyo, 101-8444, Japan
Phone: 0120-4527-66 Business hours: 9:00-17:00 (Excluding weekends and holidays)
Website: https://www.taiho.co.jp/

Manufactured and Distributed : Otsuka Pharmaceutical Factory Inc.